
Neumora Therapeutics Outlines 2026 Pipeline Strategy and Key Milestones
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Neumora Therapeutics, Inc. (NASDAQ: NMRA), a clinicalâstage biopharmaceutical company focused on developing novel therapies for neuropsychiatric and neurodegenerative diseases, has outlined its strategic priorities and anticipated milestones for 2026. The company emphasized multiple expected clinical data readouts and program advances that support its mission to redefine neuroscience drug development with treatments offering improved patient outcomes and quality of life.
Key elements of the companyâs 2026 plan include a joint topline data readout for its KOASTAL-2 and KOASTAL-3 Phase 3 studies of navacaprant in major depressive disorder in the second quarter, with a planned increase in enrollment for both trials. Neumora also intends to initiate a Phase 1 clinical program for NMRAâ215, a candidate for obesity treatment, in the first half of the year and expects to report weightâloss results by late 2026.
The company plans to advance its M4 Positive Allosteric Modulator (PAM) franchise â including NMRAâ898 and NMRAâ861 â and provide a comprehensive franchise update in midâ2026.
Already in January 2026, Neumora reported positive Phase 1b results from NMRAâ511, demonstrating a clinically meaningful effect on agitation associated with Alzheimerâs disease along with favorable tolerability.
Financially, Neumora expects its existing cash and marketable securities to support operations into the third quarter of 2027, positioning it well to execute its 2026 pipeline strategy.
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